What Obesity Debate?
This is a perfect example of how on-line weight loss “experts” can confuse and harm the American consumer…The Obesity Debate?
During a dinner conversation with a friend, the topic of laziness was brought up. From there, we some how got around to the topic of obesity. He said to me, “A great example of how bad laziness can be is obesity.”
“Excuse me,” I coughed out (almost chocking on the last bite).
“You know, obese people don’t do anything. They are fat because they are lazy,” my friend said as if from a position of authority. This was going to be a long dinner I could tell.
It turns out, my friend read an article posted on the net that started with a statement similar to my friend’s words that almost made me choke. Unfortunately, he didn’t remember the author’s name but the title was Fitness and Exercise — I haven’t found it…yet.
What blows my mind is how easily people believe what is written on a website by someone calling himself an expert! The real experts need to start making noise!
Laziness does not cause obesity. If that were so, obesity would be the norm and not considered a problem. I recently found a wonderful definition of obesity…it covers all the possibilities in one clear sentence:
The etiology of obesity is complex, determined by the interplay of genetic and environmental factors -Andrea Baessler, from her recent article in Diabetes, Jan, 2005.
There has never been a debate about what causes obesity. We have always known that obesity is multifactorial in etiology. The “real” debate topics are which environmental factors and which genes increase the risk or incidence of obesity. The rest of the article reviews recent work around two genetic links to obesity.
SREB-1 Gene
Delphine Eberle’s work (Diabetes, Aug, 2004), with the sterol regulatory element binding protein transcription factor, found that the two isoforms are linked to the “plasma leptin concentrations in American obese families.”
His group hypothesized, “…genetic variations of the SREB-1 gene could be associated with obesity and obesity-related metabolic traits such as insulin resistance, type 2 diabetes, and dyslipidemia.”
Interestingly, SREB-1 gene polymorphisms were found among obese cohorts when compared to nonobese cohorts. This means they are on to something and possibly not far from marking the SREB-1 gene as a clear link to obesity (1).
Ghrelin Receptor Gene (GHSR)
The importance of ghrelin in the central regulation of feeding has been demonstrated in animals and humans. Ghrelin increases appetite and food intake in normal subjects and patients with decreased appetite, such as those suffering from cancer cachexia. Recent evidence suggests that obesity is associated with an impairment of the entire ghrelin system (2).
Besides its biological function, the ghrelin receptor gene is located in a quantitative trait locus or QTL strongly linked to six phenotypes of obesity (1).
This is a second strong genetic association to obesity. Both groups will soon have conclusive evidence to support their arguments for SREB-1 and GHSR genetic links to obesity.
As far as I can tell, laziness wasn’t mentioned once. How many wonderful people avoid treatment because they actually believe it’s their own fault?
Educate at all costs.
Healthy Living!
Michael A. Smith, M.D.
Additional Information is available at The Weight Loss Professional
References:
Dr. Smith is the primary physician and consultant for the Weight Loss Professional Website. His interests include preventative medicine, the genetic etiology of obesity, and several others too numerous to list.
Please visit his website at weight-loss-professional.com and let him know what you think.
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Are Weight Loss Supplements Worth It?
What do you think of the hundreds of weight loss supplements out there on the shelves today? Are they worth the money? Will they actually help you lose weight? How do you know which ones are going to work for you? Is there any proof that these products work?
I’ve taken some time and researched some of the most popular product to try to find the answers for you. The truth is, most products won’t help you lose anything but money. There are a few, however, with some research behind them that prove that they actually work.
What are these supplements that work? It seems that only four products hold the best promise for those of us who want to slim down. They are Conjugated Linoleic Acid (CLA), Hydroxycitic Acid (HCA), phaseolomine, and possibly 5-HTP.
1. Conjugated Linoleic Acid, CLA, has a number of research studies behind it. It is a fatty acid that has been found to reduce cancer risks, body fat and to increase lean muscle tissue. The Journal of Nutrition reported a Scandanavian Research team found CLA to increase the lean body mass of humans and also to decrease the fat mass. Subjects also had lower blodd fat and cholestrol after taking CLA. CLA does occur naturally in meat and dairy products, but the levels are pretty low. Also, if you’re following a healthy low-fat diet, you tend to not get as much meat and dairy, so supplementation may be the answer for getting a healthy dose of CLA.
2. Hydroxycitic Acid, HCA, is derived from a fruit, Garcinia cambogia or Malabar tamarind. It seems to work by inhibiting an enzyme that converts carbohydrates to fat. It also seems to suppress the appetite. Studies on humans have had mixed results with one study showing significant weight loss in participants. Another study using a high fiber diet, showed HCA had no effect on weight loss. Critics think the high fiber diet prevented absorbtion of the HCA. So, if you’re on a high fiber diet, HCA may not be for you.
3. Phaseolomine is derived from the white kidney bean. It works by reducing your body’s absorbtion of starchy carbohydrates. Since you absorb fewer calories, you lose weight. Seems like this supplement would be great to take if you knew you were going to indulge. Research has also shown that you burn more fat while taking phaseolomine. Subjects in one study lost 10% of their body fat in 30 days. Phaseolomine is typically found in carb blocker products.
4. 5HTP works by increasing the level of Serotonin in the brain resulting in more stable emotions, better sleep and weight loss. I take 5HTP myself and have found it to be an excellent appetite suppresant as well as a mild mood booster. In one study where women were given either a placebo or 5HTP and a 1200 calorie diet, those who took the placebo lost 2.28 pounds and those who took 5HTP lost 10.34 pounds. This was accomplished in 6 weeks. Are there other supplements that work? There may be others that will stand the test of time and research, but for now these are the best non-prescription supplements I’ve found to enhance your weight loss efforts. Good luck losing the weight you want to lose!
Valerie de Armas ?2003
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